![]() Please note that the auction buybuy BABY Assets only will be held at the offices of Kirkland & Ellis LLP, 601 Lexington Avenue, New York, New York 10022 or by video conference. Auction (buybuy BABY Assets only): June 28, 2023, at 10:00 a.m., prevailing Eastern Time.Please note that the auction for all non-lease assets other than buybuyBABY asset will be held at the offices of Kirkland & Ellis LLP, 601 Lexington Avenue, New York, New York 10022 or by video conference. Auction (for all non-lease assets other than buybuy BABY assets): Jat 10:00 a.m., prevailing Eastern Time.Final Bid Deadline: June 16, 2023, at 12:00 p.m., prevailing Eastern Time.Notice of Potentially Assumed Contracts and Unexpired Leases: Jat 5:00 p.m., prevailing Eastern Time.Stalking Horse Deadline: June 12, 2023, at 5:00 p.m., prevailing Eastern Time.On April 25, 2023, the Bankruptcy Court entered an order approving the bidding procedures in connection with the sale of all or substantially all of the Debtors' assets. Please click here to download the Bar Date Order and here to download the Bar Date Notice. Governmental Bar Date: October 20, 2023Ĭlick on "Submit a Claim" above to download a proof of claim form and for more information regarding filing a claim against the Debtors.Administrative Claims Bar Date: (a) Jfor Claims incurred through June 27, 2023, (b) for all Claims arising after June 27, 2023, the 15th day of the month following the month in which the Claim arose, and (c) fourteen days following the effective date of any confirmed plan, provided, however, that notwithstanding anything to the contrary herein, counterparties to unexpired leases of non-residential real property-which leases have not been assumed, assumed and assigned, or rejected- shall be required to file Administrative Claims no later than July 21, 2023.The Bankruptcy Court has set the following deadlines for filing proofs of claim: Plan & Disclosure Statement Deadlines to File Claims Please click below to view all documents related to the Debtor's Plan & Disclosure Statement: On September 29, 2023, the effective date of the Plan occurred and the Plan was consummated. On September 14, 2023, the Bankrupcy Court entered an order approving the Disclosure Statement on final basis and confirming the Plan. The Bankruptcy Court held a combined hearing to consider confirmation of the Plan and final approval of the Disclosure Statement on Septemat 2:30 p.m., prevailing Eastern Time. On August 2, 2023, the Bankruptcy Court entered an order conditionally approving the adequacy the Disclosure Statement. ![]() The Bankruptcy Court held a hearing to consider conditional approval of the adequacy of the Disclosure Statement on Augat 2:30 p.m., prevailing Eastern Time. On July 20 & 21, 2023, the Debtors filed their Joint Plan of Reorganization (as subsequently amended, the "Plan") and the Disclosure Statement related thereto. Important Information & Dates Plan and Disclosure Statement
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![]() Plus, Vellum only works on Mac, aren't you looking for a Windows app? No notes, no snippets, no snapshots, no scrivenings, no full screen, no comments, and so on that make Scrivener (or Ulysses) so practical when writing ) That said, I don't understand how you can compare Vellum to Scrivener (or to Ulysses, or to any dedicated writing app)? I mean, sure Velum as 'chapters' that one can freely move around by drag and drop (as Word for Windows, BTW) but that's all it has to offer in regards of "managing" content. The best there is on the market, bar none, and well worth its 200€ price tag, imo if only for the time one is saving by using it. Post not showing up? Send the link to the mods.īut check out Vellum and Scrivener, because both of those are pretty damn close to what I want. r/HireAnEditor - Find editors, or advertise your own editorial services r/HireaWriter - Find writing gigs, or advertise your own writing gigs r/Writeresearch - For research into real-life areas of expertise to enhance your writing r/HomeworkHelp - Get help with homework related questions, or help others with theirs ![]() r/eroticauthors - Erotica writing discussions and advice r/fantasywriters - Discussions about writing fantasy r/DestructiveReaders - Get your work deconstructed, or help others by deconstructing theirs r/BetaReaders - Find beta readers for your work, or find something to read r/selfpublish - Publishing advice, focusing on self publishing ![]() r/PubTips - Publishing advice, focusing on traditional publication If your post has been removed and you do not know why or you have any other questions about these guidelines, please contact the moderators. Help keep the subreddit clean and on-topic by using the report feature to bring attention to rule-breaking posts. We will remove posts: berating other people for their genre/subject/literary taste adherence or non-adherence to rules calling people morons for giving a particular sort of advice insisting that their opinion is the only one worth having being antagonistic towards particular types of books or audiences or implying that a particular work is for “idiots”, or “snobs”, etc. The forum is a place where we all come together to celebrate what we do: write. Call-out threads and genre/literary-bashing Internet vigilantism and doxxing will not be tolerated. Please report any instances of offensive talk, and the mods will deal with them. Racist, homophobic/transphobic, misogynistic, ableist, and other categories of hate speech (including against “acceptable targets”) will be removed. We moderate on tone rather than language. We encourage healthy debate and discussion, but we will remove antagonistic, caustic, or otherwise belligerent posts. Treat other people with decency and respect. We prefer subjects be part of the wider writing industry or have done something more than publish a book. AMAs may not be posted without mod approval. ![]() Please limit yourself to one post per publishing cycle. Directing to a website to answer these questions is not allowed. Submission Calls Requirements/AMAsĬalls for submissions (including posts about general writing work) must include 1) payment information 2) submission deadlines 3) rights requested 4) any other relevant information. Posts focused on personal sharing may only be posted in the general discussion thread. “Low effort” posts (two lines of text, repetitive questions, etc.) will be removed. If your post invites answers that are specific to your work alone, it belongs in our brainstorming thread. We ask that users frame their posts so they are useful to multiple people. Posts should be thoughtful and useful to a broad community of writers We do not allow advertisements for your book, website, new subreddit, etc., or for you to do so on behalf of another company, outside of the self-promotion thread. Requests for school help should be posted in r/homeworkhelp, including posts about school essays or citations. Requests for writing partners may also only be posted in the critique thread. Samples of writing, whether for critique, self-promotion, or general sharing, may only be posted in the weekly self-promotion and critique thread. The moderators do reserve the right to remove posts/comments that are deemed harmful without warning and ban users depending on the severity of the infraction. Please keep these guidelines in mind for all of your posts and comments. Here's a general synopsis and explanation of /r/writing's community rules. Thank you! Before posting, check out: FAQ Our Wiki Related subreddits Want to do an AMA? Please message the mods to verify yourself before posting. Sunday: Writing Tools, Software, and Hardware Upcoming AMA posts We talk about important matters for writers, news affecting writers, and the finer aspects of the writing craft. You can bind often-used actions to device events such as rotating a USB wheel or moving a MIDI controller's slider. Pressure and tilt sensitive tablets, but also a wide range of USB or MIDI controllers. Hardware Support It includes a very unique support for various input devices out of the box. With the perspective clone tool, it's not difficult to clone objects with perspective in mind just as easily as with the orthogonal clone. Get rid of unneeded details using the clone tool, or touch up minor details easily with the new healing tool. Digital Retouching The program is ideal for advanced photo retouching techniques. Eliminate lens' barrel distortion and vignetting with a powerful filter but a simple interface. Fix perspective distortion caused by lens tilt simply choosing the corrective mode in the transform tools. Photo Enhancement Numerous digital photo imperfections can be easily compensated for using GIMP. Pressing the tab key will toggle them hidden. The interface is modulized into so called docks, allowing you to stack them into tabs or keep them open in their own window. Starting from the widget theme, allowing you to change colors, widget spacings and icon sizes to custom toolsets in the toolbox. Features and Highlights Customizable Interface Each task requires a different environment and It allows you to customize the view and behavior the way you like it. The advanced scripting interface allows everything from the simplest task to the most complex image-manipulation procedures to be easily scripted. It is designed to be augmented with plug-ins and extensions to do just about anything. GIMP is modular, expandable, and extensible. ![]() It can be used as a simple paint program, an expert-quality photo-retouching program, an online batch-processing system, a mass production image renderer, or an image format converter. ![]() It is a powerful piece of software with capabilities not found in any other free software product. GIMP (GNU Image Manipulation Program) is a freely distributed piece of software suitable for such tasks as photo retouching, image composition, and image authoring. ![]() He’s headed down a dangerous, criminal road, and it’s hard to picture a happy ending for him unless he can turn things around fairly dramatically. He wants to be a mentor to younger Greasers, but he’s barely keeping it together himself. ![]() As outside pressure mounts, he finds it more and more difficult to cope. That works with some women, but obviously not with all.Ĭhallenge… fixing his attitude. Dallas is a handsome guy, but he doesn’t know much when it comes to talking to women. Relationship Status… not tied down to anyone in particular. He also loves to antagonize the “Socs,” which is short for “Socials,” who are the wealthier, preppier group/gang in Tulsa and the arch-rivals of the Greasers. It’s not the safest way to live, of course, and it’s catching up to him. Dallas has street smarts, charm to spare, and basically does whatever he wants when he wants to do it. Dallas isn’t the kind of guy who holds down a full-time job. Profession… headed toward becoming a full-time criminal. As he tells one of them, “You think my old man gives a hang if I'm dead in a car wreck or drunk or in jail or something? He doesn't care, but that doesn't bother me.” He’s happy to be back in the company of his buddies. He’s back in Tulsa, not making much of an effort to stay out of trouble. He doesn’t have many legitimate prospects so more often than not he turns toward the less legitimate (and often criminal) opportunities that present themselves. Dallas grew up friends with Greasers and naturally became a member of the gang himself. Grew Up… in 1960’s Tulsa, Oklahoma on the wrong side of the tracks. ![]() As they say, with great power comes great responsibility, and players must learn to balance the temptation of wielding dark powers with the consequences that accompany it. Within the boundaries of this realm, players embark on an epic journey where they harness the power of life steal, a mysterious force that allows them to siphon the life force of enemies and creatures to enhance their own abilities. Unlike conventional SMP (Survival Multiplayer) realms, where players primarily focus on building, mining, and survival, "Life Steal SMP" delves into the realm of the arcane arts. "Life Steal SMP" was conceived from the idea of introducing an element of dark magic and mystical abilities into the Minecraft Bedrock experience. ![]() Delve into the thrilling world of "Life Steal SMP" and discover the mysterious powers of life steal that await. Among these realms, "Life Steal SMP" stands as an alluring and captivating Minecraft Bedrock server that offers a unique twist to the traditional gameplay. In the vast and imaginative world of Minecraft, players have explored a myriad of realms that cater to different playstyles and interests. With its diverse and talented player base, engaging lore, captivating events, and evolving landscape, the realm offers an experience like no other. "Life Night SMP" is not just another Minecraft Bedrock realm it is a testament to the power of community, creativity, and storytelling in the gaming world. Whether you're a seasoned Minecraft veteran or a newcomer to the game, "Life Night SMP" welcomes all with open arms. ![]() Players hail from various corners of the world, bringing unique perspectives and talents to the realm. Let's delve into the enchanting world of "Life Night SMP" and discover the wonders that await.Īt the heart of "Life Night SMP" lies its vibrant and diverse player base. Among these realms, "Life Night SMP" stands out as a captivating and dynamic Bedrock edition server, offering its players an immersive and unforgettable gaming experience. In the vast and creative world of Minecraft, multiplayer realms have become a thriving community where players come together to collaborate, build, and experience adventures in a shared environment. Like, subscribe, and turn on notifications to stay updated on the latest realm codes and future adventures. Join me on this thrilling journey through the "Top 10 Realms SMP for Minecraft Bedrock 1.20," and let's explore the limitless possibilities of the Minecraft universe together. From epic builds and challenging quests to vibrant communities and amazing collaborations, these realms offer an immersive and unforgettable gaming experience like never before. Welcome, Minecraft Bedrock adventurers! ? Are you searching for the ultimate realms SMP experience in the latest 1.20 update? Look no further! Join me on an epic journey as we unveil the "Top 10 Realms SMP for Minecraft Bedrock 1.20" that you don't want to miss! In this exciting video, I've carefully curated the ten most incredible realms SMP (Survival Multiplayer) servers that showcase the very best of Minecraft Bedrock edition. Top 10 Realms SMP For Minecraft Bedrock 1.20! (REALM CODE) ![]() Likewise, Villegas has successfully managed to keep that aspect of her life away from the media and limelight. She has not made a public statement or post on a boyfriend's social media to date. In terms of any romantic relationships, very little is known about Lisa Villegas. Is Lisa Villegas currently dating anyone currently? Boyfriend She spent most of her childhood alongside her siblings but there are no details about her family background. Well, she is an American meteorologist who is currently serving for a television station KOLD/KMSB TV as a chief meteorologist, based in Tucson, Arizona.īorn on 11 June 1988, in the Texas United States to the American parents, she holds an American Citizenship. Visit Glamour Path for more facts about celebrities.If you are interested in the journalism field, then you would probably hear the name, Lisa Villegas. ![]() She is active on Facebook, Instagram, and Twitter with the user name She has followers of more than 38.5K, 15.6K, and 10.8K respectively. Not only famous on television, but Lisa Villegas is also quite a known person on social media. Featuring her pet 'Biscuit' on social media. The main motive for being a member of the 'Love Vegan' campaign is to protect the animals. On the Instagram account, we can see the picture of the Steelers and Penguins. She is fond of animals and owns a dog which she named "Biscuit". She visits numerous places in the United States such as Arizona, US Virgin Island, and many more.Īfter the COVID-19 pandemic, the wanderlust (a person who loves traveling) wants to visit historical nations, Egypt, and Greece, later on, wants to make experiences like Bunjee and Swing. Lisa adores traveling and planning excursions climbing and traveling. Image Source: Twitter Travelling and Adventures A picture of Lisa Villegas wearing an 'I Love Vegan' print t-shirt. It is amazing that to know, the chief metrologist doesn't wear leather shoes and jackets, don't wear creams made of milk, often don't eat ice creams, milk, and yogurt. ![]() Likewise, she loves eating fruits, vegetables, and food made from rice and flour. Villegas has also posted a picture on her Twitter account and supporting the 'Love Vegan' advertisement. Follows Pure Vegan Fooding Habitįew people don't know that she is a pure vegan. She is currently focusing on her career to be more successful and has dedicated her time to it. Furthermore, her name has not been linked up with any guy. Relationships or Love Affairsģ2 years old, Lisa Villegas is single in relationship status and is not dating anyone yet. After having criticism, she decided to leave the television station. By listening to negative comments, Villegas removed that photo within 48 hrs. While working with a network, she posted a picture on social media where she has worn a low cut mini dress that was very form-fitting.įrom the company, she was approached to remove it because the picture may hamper the company image. The television personality has to leave CBS 11 due to one small mistake. Image Source: FlickPrime Reason Behind Leaving CBS TV Network Lisa Villegas working for KOLD/ KMSB television station. She worked in several other television channels, KRGV and KLFY TV10 as a meteorologist. She has been making her income from her career as a Chief Meteorologist for KOLD/ KMSB television station.Īt the beginning of her career, the meteorologist worked at a local Tv station and later got an opportunity on CBS television as a weather reporter. Lisa Villegas's net worth is estimated at $2 million whereas her salary is $62 thousand per annum. Here are some unknown and interesting facts about Villegas. She attended Kaplan College located in San Antonio, later graduated from Embry Riddle Aeronautical University with a bachelor’s degree in Meteorology in 2010. On 11th June 1988, Villegas was born to her parents' Joe Villegas and his wife in Texas. She previously worked at CBS 11 as a weekday and weekend morning reporter. Lisa Villegas is known as a meteorologist who has worked for KOLD/KMSB TV. ![]() 3840x2159px Nature, scenery, horizon, digital art, sunset HD wallpaper.1920x1200px Waterfall Sunset, landscape, waterfall, waterfalls, nature, grass, sunset HD wallpaper.5272圆590px Sea, sunset, red clouds, nature HD phone wallpaper.1280x720px Indian Village Scenery Painting HD wallpaper.1280x720px Natural Scenery Of Bangladesh, scenery drawing HD wallpaper.5769x3802px Nature, Trees, Sunset, Lake, Hill HD wallpaper.768x1365px Green Beautiful Nature Scenery Android, Nature Android HD phone wallpaper.2160x3840px Waterfall Autumn Forest Nature Scenery Phone iPhone, Nature Phone HD phone wallpaper.2200x1238px Anime Sunset, scenery sunset anime HD wallpaper.2160x4320px Sunset, dark theme, minimal, nature, dark, minimalist, theme, sun HD phone wallpaper.1280x800px Beautiful waterfall, tranquility, waterfall, nature, water, rocks, beauty HD wallpaper.1366x768px 1366x768 Anime Landscape, Sunset, Sky, Painting, scenery anime aesthetic HD wallpaper.1024x768px Waterfall scenery, Waterfall HD wallpaper.3500x2597px Waterfalls: Autumn Landscape Waterfall Waterfalls Nature River HD wallpaper.1920x1080px Waterfalls, Nature, Water, Forest, Jungle HD wallpaper.1280x720px easy scenery drawing step by step / moonlight drawing for beginners, nature sketch HD wallpaper.1080x1920px Waterfall Forest Nature Landscape, mobile waterfall android HD phone wallpaper.2040x1275px Nature Beautiful Waterfall, waterfall scenery HD wallpaper.3443x2403px Beach Sunset, Beach, Nature, Sunset, Ocean HD wallpaper.1080x1920px Green Beautiful Nature Scenery Android ⋆ Traxzee, green scenery android mobile HD phone wallpaper.1900x1262px waterfall in paradise, waterfall, paradise, natur, flowers HD wallpaper.753x1500px My Corner Best Far Waterfall Scenery HD phone wallpaper.1280x720px How to Draw Easy Scenery, scenery drawing HD wallpaper.1280x720px Best Sceneries For Drawing Best Drawing Scenery Pencil - Sketch Of Nature - & Background HD wallpaper.1280x720px Of Basic Easy Scenery Drawing Nature Scenery Drawing With, Cartoon Scenery HD wallpaper.2160x4320px Sunset Blue Version, aesthetic, dark theme, moon, nature, dark, minimalist, scenery, sun HD phone wallpaper.Scenery, Painting, Nature, Simple Sunset HD phone wallpaper 736x1309px Simple Minimalistic - Best Phone Background No Distractions.IPad 3, iPad 4, iPad Air, iPad iPad, iPad Mini 2, iPad Mini 3, iPad Mini 4, 9.7" iPad Pro: 2048x1536, 1536x2048 IPhone 14 Pro Max, iPhone 15 Plus, iPhone 15 Pro Max: 1290x2796 ![]() IPhone 12 Pro Max, iPhone 13 Pro Max, iPhone 14 Plus: 1284x2778 IPhone Xs Max, iPhone 11 Pro Max: 1242x2688 IPhone X, iPhone Xs, iPhone 11 Pro: 1125x2436 IPhone 6 plus, iPhone 6s plus, iPhone 7 plus, iPhone 8 plus: 1242x2208 ![]() IPhone 6, iPhone 6s, iPhone 7, iPhone 8: 750x1334 IPhone 5, iPhone 5s, iPhone 5c, iPhone SE: 640x1136 IPhone: iPhone 2G, iPhone 3G, iPhone 3GS: 320x480 Yocan took that technology and adopted it for the Yocan Orbit Vaporizer Pen. Terp pearls, sometimes referred to as dab pearls, are small pearl-like accessories used by wax concentrate consumers to improve the performance of their devices and help them achieve optimum temperature levels when dabbing. If you’ve used a dab rig or an e-rig, you’d definitely heard about terp pearls. When plugged in a wall adapter, it only takes 2.5 hours to fully charge the Yocan Orbit Vaporizer Pen. To simply put it, USB-C charging quickly charges one’s battery and prevents it from getting damaged from unstable power transfer. USB-C has certain advantages over its more dated counterparts as it offers faster charging while maintaining optimal power delivery. Speaking of charging, the Yocan Orbit Vaporizer Pen uses next-gen charging technology with USB-C. This means that light wax consumers who use their vaporizers seldomly or moderately can expect the Yocan Orbit Vaporizer Pen to put out consistent power for a day or two while those who constantly have their lips on their mouthpieces might have to plug the battery at least once a day. Those who are in need for a vaporizer that will put them through their paces need not look further as the Yocan Orbit Vaporizer Pen definitely has the power to kick them off their socks.ĭepending on your consumption pattern, the Yocan Orbit Vaporizer Pen can last you for a full day - or several days - with just a single charge. ![]() The Yocan Orbit Vaporizer Pen features a powerful 1700mAh battery that delivers more than enough juice to make the heating elements work. Yocan has used some of its advanced battery technology on its next-gen devices, devices that have been built with better features than the competition. And as always, make sure to get your vaporizers directly from the source, at Yocan Vaporizer. Interested to find out just how innovative the Yocan Orbit Vaporizer Pen can get? Read on below to see why you need to add one in your arsenal. The Yocan Orbit Vaporizer Pen features terp pearls and a coil-less quartz cup which elevates its owner’s experience and further boosts the effects of their select wax concentrates and choice extracts giving them the best session they’ve had - all while using a portable vaporizer. The Yocan Orbit Vaporizer Pen is a small and compact wax vape that brings dab rig and e-rig technology to a handheld device. This time, Yocan brings yet another innovation that we don’t typically see on wax pens. ![]() For years, the Chinese vaporizer company has always been the go-to for affordable and reliable wax pens, dry herb vapes, and oil vaporizers allowing many consumers to enjoy and experience the latest innovations in vaping without actually breaking the bank. Our Beaverton-Hillsdale location proudly upholds Nectar’s mission of providing accessibility, convenience, and great prices on cannabis.Yocan has always been one to revolutionize the vaping industry. ![]() To find a location near you, order online for pick-up, and stay up to date on all things Nectar, visit us online at Opened in August 2017, Nectar’s Beaverton-Hillsdale location is conveniently located off the SW Beaverton-Hillsdale Highway. With locations spread throughout Portland and stores dotting the map across Oregon, our expansion continues with one goal in mind: Assuring the nearest Nectar is never too far away and is always there for our customers. Nectar is committed to being open 365 days a year. ![]() Our dispensaries feature an outstanding selection of products from the best cannabis producers in Oregon, offered at the best prices. Our 100% satisfaction guarantee is just one of the many reasons we have quickly grown into the largest recreational cannabis dispensary chain in Oregon. Since opening in 2013, Nectar’s customer-first approach has set us apart. ![]() ![]() Uphill efficiency: The Ergo Televators reduce fatigue and increase traction on the slopes with an ergonomic design that blends with a grip.Adaptability to all conditions: additional modular floating queues allow the maneuverability of a smaller primary snow rack with additional floating on request of optional 13 cm queues.Paragon Attacks: the comfortable frost-resistant mesh strap securely wraps a wide range of boots for maximum control, while the footrests offer a fast and precise foot alignment.Durable: the injection molded plastic deck resists abusive conditions and offers a thin torque bending under the feet for an excellent purchase.External traction: Aggressive perimeter teeth and DTX ramps in durable steel offer an advanced traction, especially on beams and in difficult conditions. The MSR Revo Ascent is a mountaineering-style snowshoe that has lightweight plastic decking, a.With a fit similar to a glove that eliminates pressure points, the attack net strap offers excellent comfort and safety on technical terrain.īelow the feet, the ExoTractTM platform pairs the external steel teeth with the twisted bending of the plastic for a traction that inspires confidence. The snowshoes Revo Ascent MSR offer exceptional resistance on aggressive soils and are now equipped with new Paragon attacks for maximum foot control. Completing the kit, the quality carry/storage. Our DynaLock Explore three-section poles offer fast, reliable adjustments and pack small for easy stowing. 25 results for 'msr revo ascent snowshoes' Results Price and other details may vary based on product size and color. ![]() MSR - Revo Ascent W, snowshoes / snowshoes woman It features our Evo Ascent snowshoestrue all-around performers providing workhorse durability, all-terrain traction, and Televator heel lefts to assist with climbing steeper slopes. ![]() In spite of these indications, LABA/ICS inhalers remain the second most commonly prescribed first-line treatments (after LAMA monotherapy) across the range of COPD severities, because its use has been associated with an increased risk of pneumonia. On the other hand, LABA-ICS combinations are indicated for patients with severe-to-very-severe disease and a history of repeated exacerbations. Additionally, they prevent exacerbations and increase exercise endurance by reducing pulmonary hyperinflation and dyspnoea. Long-acting bronchodilator combinations (LAMA/LABA) have been identified as the initial drugs of choice for patients with more severe dyspnea, airflow obstruction, and hyperinflation. Use of LABA-LAMA inhalers are crucial to symptom management in COPD, improving lung function and health-related quality of life. As combination LABA/LAMA inhalers are now widely available, there is a need for welldesigned RCTs to investigate whether ICS provides any added therapeutic benefit. However, results for the incidence of severe pneumonia requiring hospitalization were better with LABA-LAMA (HR, 0.66 0.41–1.05), particularly in the on-treatment analysis (HR, 0.66 0.50–0.87). A lower dose, twice daily regimen for a LABA/LAMA has also been shown to improve. In multivariable Cox analysis the respective hazard ratios (HRs) for moderate and severe COPD exacerbations associated with LABA-LAMA initiation vs LABA-ICS initiation were 1.04 (95 percent CI, 0.90–1.20) and 0.94 (0.65–1.36). LABA/LAMA combinations are best evaluated on an individual patient basis. LAMA containing inhalers may have an advantage over those without a LAMA for preventing COPD exacerbations based on the rank statistics. There was no significant difference in the incidence of exacerbations between the two groups. The LABA/LAMA combination was the highest ranked treatment group to reduce COPD exacerbations although there was some uncertainty in the results. ![]() Researchers used data from the United Kingdom’s Clinical Practice Research Datalink and identified 1,977 initiators of LABA-LAMA and 1,977 matched initiators of LABA-ICS.Īll patients were aged ≥55 years and followed for 12 months for the occurrence of a moderate or severe COPD exacerbation and severe pneumonia. Long-acting beta 2-agonist (LABA) plus long-acting muscarinic antagonist (LAMA) combinations compare with inhalers containing both LABA and corticosteroid (LABA-ICS) in terms of reducing chronic obstructive pulmonary disease (COPD) exacerbations, although the LAMA-LABA combination is more favourable as it is associated with fewer episodes of severe pneumonia, according to a study. |
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